Kappa Opioid Receptor Distribution and Function in Primary Afferents
نویسندگان
چکیده
منابع مشابه
GR89,696 is a kappa-2 opioid receptor agonist and a kappa-1 opioid receptor antagonist in the guinea pig hippocampus.
Receptor binding studies and electrophysiological studies demonstrated the existence of at least two kappa opioid receptors, which have been designated kappa-1 and kappa-2. Several agonists and antagonists are selective for the kappa-1 receptor whereas no known ligands are selective for the kappa-2 receptor. In this study, the kappa opioid GR89,696 was tested in the guinea pig hippocampal slice...
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ژورنال
عنوان ژورنال: Neuron
سال: 2018
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2018.08.044